Comparative characteristics of the treatment of patients with chronic generalized periodontitis against the backdrop of a reduced antioxidant protection of the body

Authors

  • А. В. Самойленко
  • А. Є. Горшкова

DOI:

https://doi.org/10.33295/1992-576X-2020-1-54

Keywords:

treatment of chronic generalized periodontitis, selenium

Abstract

Summury. Data on the pathogenetic role of lipid peroxidation indicates the advisability of antioxidant therapy aimed at modifying local processes in the affected periodontium in order to eliminate their destructive effect on periodontal tissues. The question of the use of selenium preparations in the complex treatment of chronic generalized periodontitis remains opened. The drug has a positive effect on the clinical course of periodontal tissue diseases and the state of antioxidant protection of the oral fluid.
Goal: to increase the effectiveness of treatment of patients with chronic generalized periodontitis by using selenium preparations.
Research materials and methods. To solve these problems, we examined 90 patients with chronic generalized periodontitis between the ages of 27 and 43 years. Among the examined patients there were 47 (52.2 %) patients with chronic generalized periodontitis of grade I and 43 (47.8 %) patients diagnosed with chronic generalized periodontitis of grade II. Patients were divided into three groups of 30 people. All patients were examined according to the standard scheme including complaints, life anamnesis information, objective data, and special indices: oral hygiene was performed using the Silness-Loe indices, Stellard, gingivitis severity using the PMA index, blood index clear for H.R. Muhlemann, A.S. Mazor (1958), periodontal index (Russell, 1956), index of need for treatment of periodontal diseases CPITN.
Results and Discussion. The patients of the first group with chronic generalized periodontitis were treated according to the traditional scheme. Patients of the second group with chronic generalized periodontitis were treated according to a similar algorithm, with an additional usage of an oily solution of retinol acetate, topically applied -tocopherol acetate, ascorbic acid by ultrafonophoresis. For the treatment of patients of the third group we used added the mineral complex «Selenium active». In the first group there was a decrease in the Silness-Loe index to 0.74±0.06 (by 63.9 %; p < 0.001), in the second to 0.61±0.07 (by 69.8 %; p < 0.001), the most significant changes occurred in patients in the third group – up to 0.21±0.01 (89.6 %; p < 0.001).The Stellard index also dropped significantly (p < 0.001) in the first group from 2.14±0.09 to 0.79±0.07, in the second – from 2.11±0.09 to 0.81±0.04, in the third – from 2.10±0.09 to 0.60±0.03. Scale index decreased in patients of the first group to 0.26±0.01 (p < 0.001), the second – 0.24±0.01 (p < 0.001), the third – 0.21±0.01 (p < 0.001). After treatment, Muhleman H.R bleeding index was 1.01 0.06 in the first group, 0.61±1.58 in the second group, and 0.21±0.02 in the third group. The periodontal index showed an improvement in the clinical picture among patients of the first group – 0.99±2.28, the second – 0.67±0.04, and the most significant changes occurred among patients of the third group – 0.24±0.02. The index of need for treatment of periodontal diseases CPITN in the first group decreased from 2.45±0.10 to 1.01±0.02, in the second – from 2.41 0.10 to 0.75±0.04, in the third – from 2.38±0.10 to 0.45±0.04. The PMA index after treatment in third group of patients decreased from 61.43 ± 1.98 to 18.35 ± 0.49. Although periodontal tissue improvement occurred in all patients, changes in the third group were more significant, indicating that the proposed regimen was effective.
Conclusions. The inclusion of selenium in the scheme of complex treatment of chronic generalized periodontitis significantly increases the effectiveness of it, which is determined by the improvement of the clinical course of thedisease.
Key words: treatment of chronic generalized periodontitis, selenium.

Author Biographies

А. В. Самойленко

А.В. Самойленко – ДЗ «Дніпропетровська медична академія»,м. Дніпро, Україна.

А. Є. Горшкова

А.Є. Горшкова – ДЗ «Дніпропетровська медична академія»,м. Дніпро, Україна.

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Published

2020-03-24

Issue

Section

PARADONTOLOGY