Effect of periodontal treatment by one stage full mouth scaling and root planing with and without azithromycin
DOI:
https://doi.org/10.33295/1992-576X-2019-4-30Keywords:
periodontitis, one stage full mouth scaling and root planing, antibiotics, azithromycinAbstract
Background and Objective. The study examines efficacy of azithromycin as an adjunct to non-surgical treatment on clinical parameters and body temperature.
Methods. 31 patients with chronic severe generalized periodontitis (according to New American Academy of Periodontology Classification: Stage 3 or 4, Grade B) were randomly assigned to 2 groups - comparative (one stage full mouth scaling and root planing with azithromycin, n =1 6) and control (one stage full mouth scaling and root planing without azithromycin, n = 15). Probing depth, clinical attachment level, BOP and plaque index were exanimated at baseline and 6 months after treatment, and body temperature.
Results. No statistically significant differences were observed between comparative and control groups at clinical parameters 6 months after treatment (P < 0.05). Both therapies reduced the periodontal pockets and decreased the clinical attachment. The body temperature increased significantly in patients of the control group.
Сonclusions. On the basis of present findings, it can be concluded that azithromycin as an adjunct to non-surgical treatment, not demonstrated additional benefits compared to just one stage full mouth scaling and root planing in atients with chronic severe generalized periodontitis. The use of azithromycin was effective in preventing the elevation of the body temperature after full mouth scaling and root planing.
Key words: periodontitis, one stage full mouth scaling and root planing, antibiotics, azithromycin.
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https://onlinelibrary.wiley.com/doi/abs/10.1111/jre.12680 DOI: 10.1111/jre.12680
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