The Correction of Lysozyme in Mixed Saliva of Chronic Maxillary Sinusitis Patients with Oral Galvanosis

Authors

DOI:

https://doi.org/10.33295/1992-576X-2025-1-103

Keywords:

chronic maxillary sinusitis, maxillary sinus, galvanic pathology, saliva, lysozyme, Lysobact, galvanosis, metal inclusions, inflammation, osteomyelitis

Abstract

Purpose: to determine the effectiveness of using a drug containing lysozyme hydrochloride to normalize the level of lysozyme enzyme in the mixed saliva of patients with chronic odontogenic maxillary sinusitis with oral galvanosis.

Materials and Methods. 31 patients with chronic odontogenic maxillary sinusitis with galvanosis in the oral cavity were examined and underwent immunological and general clinical examination methods.

Results. Based on the examination of patients with odontogenic maxillary sinusitis in the presence of galvanosis in the oral cavity, a temporary immunodeficiency was detected, which was eliminated by treatment with Lisobact®. In all operated patients in the early postoperative period, there was no such complication as the inflammatory infiltration of soft tissues in the postoperative wound area.

Conclusions. The conducted examination gives us reason to recommend the drug “Lisobakt®” not only for normalizing the local nonspecific resistance of the body, but also allows you to eliminate the appearance of early inflammatory complications and reduce the development of late inflammatory complications (limited destructive osteomyelitis of the alveolar process of the upper jaw) by 2.5 times in the postoperative period of treatment of patients.

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Author Biographies

Oleksiy O. Tymofeiev, P. L. Shupyk National University of Health Care

Doctor of Medical Sciences, Professor, Head of the Department of Maxillofacial Surgery, Honored Worker of Science and Technology of Ukraine

A. M. Cherednichenko, P. L. Shupyk National University of Health Care

postgraduate student of the Department of Maxillofacial Surgery

Oleksandr O. Tymofeiev, Shupyk National Healthcare University of Ukraine

Doctor of Medical Sciences, Professor of the Department of Dentistry

M. O. Yaryfa, Private higher educational institution "Kyiv Medical University"

Candidate of Medical Sciences, Associate Professor of the Department of Surgical Dentistry and Maxillofacial Surgery 

References

Motavkyna, N.S., Kovalev, V.M., Sharonov, A.S. (1979). Mykrometod kolychestvennoho opredelenyia lyzotsyma. Laboratornoe delo, 12, 722–724. [In Russian].

Tymofieiev, O.O. (2022). Shchelepno-lytseva khirurhiia. Kyiv: Medytsyna. [in Ukrainian].

Tymofeev, A. A. (2020). Cheliustno-lytsevaia khyrurhyia y khyrurhycheskaia stomatolohyia: uchebnyk. Kyiv: Medytsyna. Kn. 1. [In Russian].

Tymofeev, A. A. (2022). Cheliustno-lytsevaia khyrurhyia y khyrurhycheskaia stomatolohyia: uchebnyk. Kyiv: Medytsyna. Kn. 2. [In Russian].

Tymofieiev O. O. (2024). Khirurhichna stomatolohiia ta shchelepno-lytseva khirurhiia: pidruchnyk. Lviv: Marchenko T. V. T. 1. [In Ukrainian].

Tymofieiev, O. O., Cherednichenko, A. M. (2024). Vmist lizotsymu u zmishanii slyni v dynamitsi likuvannia khvorykh na khronichnyi odontohennyi haimoryt za naiavnosti halvanichnoi patolohii u porozhnyni rota. Suchasna stomatolohiia, 2, 61–64. DOI: https://doi.org/10.33295/1992-576X-2024-2-61. [In Ukrainian].

Published

2025-02-28

How to Cite

Tymofeiev О., Cherednichenko А. М., Tymofeiev О., & Yaryfa . М. О. (2025). The Correction of Lysozyme in Mixed Saliva of Chronic Maxillary Sinusitis Patients with Oral Galvanosis. Actual Dentistry, (1), 103–106. https://doi.org/10.33295/1992-576X-2025-1-103

Issue

Section

MAXILLOFACIAL SURGERY AND SURGICAL DENTISTRY