Порівняльна оцінка гемодинаміки периімплантних тканин на етапах лікування стоматологічних пацієнтів із негайним і відстроченим навантаженням незнімними ортопедичними конструкціями

Ι. Yanishen; O. Fedotova

doi:10.33295/1992-576X-2025-3-126

Authors

Ι. Yanishen Kharkiv National Medical University https://orcid.org/0000-0003-4278-5355
O. Fedotova Kharkiv National Medical University https://orcid.org/0000-0001-9421-9262

DOI:

https://doi.org/10.33295/1992-576X-2025-3-126

Keywords:

glass ceramic coating, dental implants, osseointegration, microcirculation, immediate loading, fixed orthopedic structures

Abstract

The traditional approach to dental implantation assumes that to achieve proper osseointegration, implants should remain without any load for 3–4 months on the lower jaw and 4–5 months on the upper jaw. However, reducing the treatment period is desirable for both patients and dentists.
This study aimed to improve the quality of life for dental patients with dentition defects by reducing the time required for osseointegration when using implants coated with a new domestic bioactive calcium phosphate silicate glass ceramic, while also studying the hemodynamic indicators of peri-implant tissues under control conditions.
Materials and methods of the study. Blood microcirculation studies were performed in 20 patients of the leading group, in which implants with bioactive calcium phosphate silicate glass ceramic coating were integrated (9 women, 11 men, age from 21 to 62 years) and in 19 patients of the control group (10 women, nine men, age from 19 to 58 years), who underwent implantation according to the standard protocol for the use of conventional implants.
Results of the study. In patients of the leading group, the values fluctuated slightly throughout the survey, from (10.32 ± 0.61) p. u. and a maximum of (12.47 ± 0.21) p. u., and at no stage did they differ significantly between delayed and immediate prosthetics, returning at stage 4 almost to the initial figures. As for the results of the control group, the values of all stages were within the range of (11.08 ± 0.45) p. u. to (15.23 ± 0.76) p. u. and significantly worsened (p < 0.05) at the 2nd stage of the study. Although the indicators no longer showed a significant difference after 6 months compared to the 1st stage, the detected instability still significantly affects the rate of osseointegration. Measurements taken before implantation revealed no significant difference in microcirculation among all subjects, indicating equal conditions. However, after one month, data were obtained on a substantial (p < 0.05) difference between the results of the leading and control groups for both subgroups — (12.3 ± 0.3) p. u. and (14.7 ± 0.69) p. u. respectively.
Conclusions. Thus, the study indicated that when using implants coated with a new domestic bioactive calcium phosphate silicate glass ceramic, even with immediate loading, changes in the microcirculatory bed of peri-implant tissues at all stages of the study do not differ significantly.

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Author Biographies

Ι. Yanishen, Kharkiv National Medical University

Doctor of Medical Sciences, Professor, Head of the Department of Orthopedic Dentistry

O. Fedotova, Kharkiv National Medical University

PhD, Associate Professor of the Department of Prosthetic Dentistry

References

Chen J, Cai M, Yang J, Aldhohrah T, Wang Y. (2019). Immediate versus early or conventional loading dental implants with fixed prostheses: A systematic review and meta-analysis of randomized controlled clinical trials. J Prosthet Dent, 122(6): 516–536. DOI: https://doi.org/10.1016/j.prosdent.2019.05.013.

Yanishen ІV., Fedotova OL., Savielieva NM., Khlystun NL., Pogorila AV. et al. (2022). Study of the influence of biocompatible construction materials on indicators of oral fluid of patients with an allergic status during orthopedic treatment with removable prostheses. World of Medicine and Biology, 18(82): 201–205. DOI: https://doi.org/10.26724/2079-8334-2022-4-82-201-205.

Romanos GE, Aydin E, Locher K, Nentwig GH. (2016). Immediate vs. delayed loading in the posterior mandible: a split-mouth study with up to 15 years of follow-up. Clin Oral Implants Res. 27(2): е74–9. DOI: https://doi.org/10.1111/clr.12542.

Esposito M, Siormpas K, Mitsias M, Bechara S, Trullenque-Eriksson A, Pistilli R. (2016). Immediate, early (6 weeks) and delayed loading (3 months) of single implants: 4-month post-loading from a multicenter pragmatic randomised controlled trial. Eur J Oral Implantol, 9(3): 249–260. PMID: 27722223.

Omura Y, Kanazawa M, Sato D, Kasugai S, Minakuchi S. (2016). Comparison of patient-reported outcomes between immediately and conventionally loaded mandibular two-implant overdentures: A preliminary study. J Prosthodont Res. 60(3): 185–92. DOI: https://doi.org/10.1016/j.jpor.2015.12.010.

Chidagam PRLV, Gande VC, Yadlapalli S, Venkata RY, Kondaka S, Chedalawada S. (2017). Immediate Versus Delayed Loading of Implant for Replacement of Missing Mandibular First Molar: A Randomized Prospective Six Years Clinical Study. J Clin Diagn Res, 11(4): ZC35–ZC39. DOI: https://doi.org/10.7860/JCDR/2017/26362.9663.

Giacomel MC, Camati P, Souza J, Deliberador T. (2017). Comparison of Marginal Bone Level Changes of Immediately Loaded Implants, Delayed Loaded Nonsubmerged Implants, and Delayed Loaded Submerged Implants: A Randomized Clinical Trial. Int J Oral Maxillofac Implants, 32(3): 661–666. DOI: https://doi.org/10.11607/jomi.5353.

Kern JS, Kern T, Wolfart S, Heussen N. (2016). A systematic review and meta-analysis of removable and fixed implant-supported prostheses in edentulous jaws: post-loading implant loss. Clin Oral Implants Res, 27(2): 174–95. DOI: https://doi.org/10.1111/clr.12531.

Mikhailova, V. V., Libikh, D. A. (2014). Dynamics of changes in microcirculation parameters of the oral mucosa in patients with paresthesia during orthopedic dental treatment. Periodontology, 3(72): 51–53. [ Михайлова, В. В. Динаміка змін показників мікроциркуляції слизової оболонки ротової порожнини у пацієнтів з парестезією в процесі ортопедичного стоматологічного лікування. Пародонтологія, 3(72): 51–53. ].

Zhang S, Wang S, Song Y. (2017). Immediate loading for implant restoration compared with early or conventional loading: A meta-analysis. J Craniomaxillofac Surg, 45(6): 793–803. DOI: https://doi.org/10.1016/j.jcms.2016.05.002.

Moraschini V, Porto Barboza E. (2016). Immediate versus conventional loaded single implants in the posterior mandible: a meta-analysis of randomized controlled trials. Int J Oral Maxillofac Surg, 45(1): 85–92. DOI: https://doi.org/10.1016/j.ijom.2015.07.014.

De Bruyn H, Christiaens V, Doornewaard R, et al. (2017). Implant surface roughness and patient factors on long-term peri-implant bone loss. Periodontol 2000, 73(1): 218–227. DOI: https://doi.org/10.1111/prd.12177.

Atieh MA, Alsabeeha N, Duncan WJ. (2018). Stability of tapered and parallel-walled dental implants: A systematic review and meta-analysis. Clin Implant Dent Relat Res, 20(4): 634–645. DOI: https://doi.org/10.1111/cid.12623.

Pigozzo MN, Rebelo da Costa T, Sesma N, Laganá DC. (2018). Immediate versus early loading of single dental implants: A systematic review and meta-analysis. J Prosthet Dent, 120(1): 25–34. DOI: https://doi.org/10.1016/j.prosdent.2017.12.006.

Ribeiro AKC, Veríssimo AH, Lemos LM, Bezerra ADS, de Almeida ÉO, Carreiro ADFP. (2024). Complications and Patient-Centered Outcomes of an Implant- Supported Single Crown After Immediate and Delayed Loading: A Systematic Review and Meta-analysis. Int J Oral Maxillofac Implants, 39(4): 137–156. DOI: https://doi.org/10.11607/jomi.10593.

Ribeiro AKC, Costa RTF, Vasconcelos BCDE, de Moraes SLD, Carreiro ADFP, Pellizzer EP. (2024). Patient-reported outcome measures and prosthetic events in implant-supported mandibular overdenture patients after immediate versus delayed loading: A systematic review and meta-analysis. J Prosthet Dent, 131(5): 833–840. DOI: https://doi.org/10.1016/j.prosdent.2022.03.015.

Cao ZL, Li X, Lin LJ, Chen YH. (2021). Immediate or delayed loading protocols for two-implant mandibular overdentures: A systematic review and meta-analysis of randomized controlled trials. J Prosthet Dent, 126(6): 742–748. DOI: https://doi.org/10.1016/j.prosdent.2020.09.011.

Yanishen IV, Zapara PS, Fedotova OL, Khlistun NL, Saliya LG. (2022). Study of hemodynamics of the mucous membrane of the prosthetic area at the stages of treatment of patients with removable dentures according to the improved technique. Pol Merkur Lekarski, 50(295): 13–15. PMID: 35278291.

Ognev V.A. (2023). Biological statistics. Kharkiv: KhNMU, 316 p. [ Огнєв В. А. (2023). Біологічна статистика. Харків : ХНМУ, 316 с. ].