Найближчі результати застосування медикаментозної композиції для лікування генералізованого пародонтиту у хворих на цукровий діабет

A. Lenihevych

doi:10.33295/1992-576X-2025-5-4

Authors

A. Lenihevych Bogomolets National Medical University, Kyiv, Ukraine https://orcid.org/0009-0008-1949-5775

DOI:

https://doi.org/10.33295/1992-576X-2025-5-4

Keywords:

generalized periodontitis, diabetes mellitus, drug composition, clinical studies

Abstract

Summary. Investigations have shown that generalized periodontitis is often associated with endocrine diseases such as diabetes mellitus. Given the close relationship between diabetes mellitus and generalized periodontitis, it is essential to improve the effectiveness of prevention and treatment for patients with generalized periodontitis who have manifestations of diabetes mellitus.
Aim. To determine the effectiveness of the immediate results of using a drug composition for the treatment of generalized periodontitis in patients with diabetes mellitus.
Material and methods. For clinical and laboratory studies, a group of 50 patients with generalized periodontitis of I-II degree, of chronic course, on a background of diabetes mellitus, and young age (20-45 years) was selected. The comparison group consisted of 20 patients with generalized periodontitis of I-II degree, of chronic course, on a background of diabetes mellitus. The control group consisted of 20 patients with generalized periodontitis without manifestations of diabetes mellitus or other general somatic diseases.
Complex treatment of generalized periodontitis was performed in accordance with the protocols for the treatment of dental diseases approved by the Ministry of Health of Ukraine [2004]. Treatment of periodontal lesions in the leading clinical group was performed using the proposed medicinal composition as part of complex therapy.
Results. Examination of patients in the comparison group conducted before the start of complex treatment showed a picture of periodontal condition similar to that in patients in the leading group. Complex treatment significantly improved the hygienic condition (OHI-S), reduced the manifestations of inflammation (PMA), and reduced the bleeding index on probing (BOP). The clinical level of attachment loss remained unchanged after treatment.
Conclusions. The comprehensive treatment of patients in the leading, comparison, and control groups showed that the treatment in the leading group was more effective. The index assessment of the periodontal condition of patients in the leading group is practically similar to that of patients in the control group, i.e., people without a background disease of diabetes mellitus. The obtained data indicate the effectiveness of the proposed treatment of patients with generalized periodontitis on the background of diabetes mellitus.

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